Pharmacokinetics of cefmetazole in elderly patients and healthy volunteers.
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منابع مشابه
Comparative Pharmacokinetics of Levofloxacin in Healthy Volunteers and in Patients Suffering from Typhoid Fever
The aim of this study was to characterize the effect of typhoid fever on pharmacokinetic parameters of levofloxacin (LF) and compare the pharmacokinetic parameters of the said antibiotic in healthy human volunteers and patients with typhoid fever. Total of 12 subjects were divided into two groups “A” (healthy volunteers) and “B” (typhoid patients). Single oral dose of LF 500 mg was given and 5 ...
متن کاملComparative Pharmacokinetics of Levofloxacin in Healthy Volunteers and in Patients Suffering from Typhoid Fever
The aim of this study was to characterize the effect of typhoid fever on pharmacokinetic parameters of levofloxacin (LF) and compare the pharmacokinetic parameters of the said antibiotic in healthy human volunteers and patients with typhoid fever. Total of 12 subjects were divided into two groups “A” (healthy volunteers) and “B” (typhoid patients). Single oral dose of LF 500 mg was given and 5 ...
متن کاملPharmacokinetics of ampicillin-sulbactam in healthy elderly and young volunteers.
The pharmacokinetics of ampicillin-sulbactam in elderly subjects (65 to 85 years; group 3, n = 8), compared with those in middle-aged (41 to 64 years; group 2, n = 8) and younger (20 to 40 years; group 1, n = 8) subjects, were investigated. A single 2-g dose of ampicillin combined with 1 g of sulbactam in 60 ml of intravenous solution was administered to each subject over a 30-min period. Blood...
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BACKGROUND AND OBJECTIVES: The combination of cromolyn and ibuprofen is being investigated as a treatment for early Alzheimer's disease (AD). This study investigated the pharmacokinetics, safety, and tolerability of cromolyn and ibuprofen co-administration in healthy elderly adult volunteers. METHODS In this open-labeled study, 26 subjects, aged 55-75 years, received co-administration of inha...
متن کاملPharmacokinetics of sparfloxacin in healthy volunteers and patients: a review.
In Caucasian volunteers and patients plasma sparfloxacin concentrations reached a peak of 1.2-1.5 mg/L between 3 and 6 h after a single 400 mg dose; T1/2 ranged from 16 to 22 h. The peak plasma concentration and the area under the plasma concentration-time curve exhibited dose-related increases but a slight decrease in the extent of absorption was observed following administration of doses abov...
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ژورنال
عنوان ژورنال: Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics
سال: 1986
ISSN: 1882-8272,0388-1601
DOI: 10.3999/jscpt.17.569